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Our renal models, including the aProximate Proximal Tubule Cell (PTC) system, provide translational insight into kidney safety, metabolism, and transport, helping sponsors build confidence in their data before clinical trials

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Whilst these medications demonstrate significant efficacy in achieving weight reduction, gastrointestinal side effects are amongst the most commonly reported adverse reactions

In uveal melanoma, it has been demonstrated that lactate supplementation to in vitro cultured cells increases the mRNA expression of factors involved in mitochondria biogenesis and activity, suggesting a metabolic shift towards an oxidative metabolism [32]

nausea and vomiting) than men per kilogram of weight lost (Fig