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EbrahimiFYaoJHagstrmHStephanssonOSunJBergmanDet al

To further elucidate the potential molecular mechanisms by which SAC alleviates UC, this study aims to investigate how SAC targets the Keap1/Nrf2/GPX4 signaling pathway to suppress ferroptosis in intestinal epithelial cells during UC, thereby restoring intestinal barrier integrity

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CHE often presents with nonspecific symptoms, and differentiation from other conditions can be challenging, resulting in uncertainty regarding treatment indication in some cases [121]

The extract displayed dose- and time-dependent antiproliferative effects on A549 cells, with IC 50 decreasing from 340.63 g/mL at 24 h to 107.08 g/mL at 72 h, indicating enhanced cytotoxicity over time