756 , 757 , 758 The signs of cognitive impairment that PCPs may detect include overt functional and communication changes as well as more subtle signs, such as irregularities in medication or appointment adherence, loss of control of chronic disease, weight loss, or increased emergency department visits or hospitalizations
The study, titled Combined Supplementation of S-Nitro glutathione and Glutathione Improves Glycaemic Control in type 2 Diabetic Rats, was led by masters graduate from the Faculty of Medical Sciences at the University of the West Indies (UWI) Mona campus, Amarley Wright
A number of approaches targeting deficient GCase activity in GBA-PD have reached the stage of clinical phase 2/3 trials including orally active GCase chaperones to enhance enzymatic activity, substrate reduction therapies modelling current treatment of Gauchers disease and GBA gene therapy (Table 5)
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