Particularly if someones got type 2 diabetes, they should be having once-a-year back-of-the-eye checks and understanding whether they might have additional risk factors, including their cup-to-disc ratio. According to the Database of Adverse Event Notifications, 36 cases of optic ischaemic neuropathy with GLP-1s have been identified, including 23 for semaglutide, 10 for tirzepatide and three for liraglutide
* Axxam hereby acknowledges that the NCI-H716 cell line (ATCC Ref
If tirzepatide is not suitable, the provider may recommend compounded semaglutide as an alternative or explain why treatment is not recommended
A more flexible, individualized approach one that values glycemic remission, metabolic flexibility, and fat distribution alongside the scale might help engage more people and improve long-term outcomes
The STEP trials (Semaglutide Treatment Effect in People with obesity) showed that weekly semaglutide injections produced average weight loss of 15.3 kg over 68 weeksapproximately 15% of body weight