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Regardless of their impact on glucose regulation, these medications prevent the deterioration of kidney function by lowering glomerular hypertension, which is mediated by tubuloglomerular feedback (280)

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Some of the metabolic disorders can be diagnosed at the early stage of the disease based on relevant examinations

The authors suggested that coenzyme Q10 deficits can be a cause of migraine headaches in children and adolescents, thus stressing the importance of determining coenzyme Q10 deficiency levels in those patients and respective supplementation [81] (Table 2)